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0003319708319645v1
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First published on May 29, 2008, doi:10.1177/0003319708319645

Angiology 2008;59:54S.

A more recent version of this article appeared on August 1, 2008

Article

Influence of Aging and Menopause on Lipids and Lipoproteins in Women

Genovefa D. Kolovou, MD* and Helen G. Bilianou, MD

Onassis Cardiac Surgery Center

* To whom correspondence should be addressed. E-mail: genovefa{at}kolovou.com.


  Abstract
The actions of endogenous estrogens on the cardiovascular system can be mediated directly on the vessels or indirectly through the modulation of cardiovascular risk factors. Aging and menopause are the main causes that lead to an adverse lipid profile in women. The influence of age on prevalence of increased plasma triglyceride levels and on larger variation in fasting triglyceride levels has been reported in both genders. However, the increased prevalence of increased cholesterol with age was only found in women. The high-density lipid cholesterol level is higher in women than in men throughout all ages. Obesity may also exaggerate the unfavorable lipid profile in aging and/or menopausal women. In the last decades the management of the menopausal women has been a subject of concern for medical scientific groups. In this review, the current understanding of an influence of age and menopause on lipids and lipoproteins concentration in women will be analyzed.


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